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Transient Neonatal Diabetes Mellitus (TNDM)

Transient neonatal diabetes mellitus (TNDM) appears at birth but usually disappears after 3-6 months (it can last up to 12 to 18 months of age). About half of children with TNDM will redevelop diabetes later in life (relapsed diabetes).

TNDM is typically treated with insulin injections.  However, the best treatment for relapsed diabetes is unclear, with some people requiring multiple daily injections of insulin and others doing well on pills or a combination of insulin and pills.

It is critical for babies with TNDM and older individuals with relapsed diabetes to remain under the care of a specialist, who can determine the most appropriate course of treatment.