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Neonatal Diabetes

Neonatal Diabetes

Anyone diagnosed with diabetes before 6 months of age is very likely to have monogenic neonatal diabetes and should be tested.

Occasionally, people diagnosed with diabetes between 6 and 12 months of age have also been found to have a monogenic cause.  Therefore, testing should also be considered in these cases.

Neonatal diabetes can be permanent (permanent neonatal diabetes mellitus, PNDM) or transient (transient neonatal diabetes mellitus, TNDM). In PNDM, the diabetes requires treatment for the person’s entire life. In TNDM, the diabetes may go away and no longer require treatment after the first few months of life. However, the diabetes will often return later in life.  It is very important to have genetic testing done to help guide treatment, prognosis and monitoring for diabetes recurrence.

  • Learn more about PNDM and TNDM.

People with monogenic neonatal diabetes are often misdiagnosed as having type 1 diabetes. However, they might experience complications not commonly linked to type 1 diabetes, such as learning and developmental problems.

People with monogenic diabetes might respond to treatments other than insulin, including sulfonylureas – pills that prompt the body to start producing adequate levels of insulin on its own.

  • Do you believe that you, your child or a family member might have been born with monogenic diabetes? Find out where to go for testing.

The Kovler Diabetes Center has a Neonatal Diabetes Registry that helps researchers study neonatal diabetes and uncover diabetes patterns in families. If you, your child, or a family member has diabetes that was diagnosed at or before 12 months of age (even if the diabetes was “transient,” or temporary), you may be eligible to participate in our studies.

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    he’s one in half a million and one week old! | How's Cooper? says:

    [...] more info check out the research site from the University of Chicago: http://monogenicdiabetes.uchicago.edu/what-is-monogenic-diabetes/neonatal-diabetes/. You will find the information about neonatal diabetes under the drop down menu titled “What [...]

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